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Monitoring Anesthesia in Laboratory Animals

During anesthesia the patient should be monitored to insure adequate circulation, oxygenation, and ventilation. Suggestions for monitoring anesthetized veterinary patients have been developed the the American Veterinary Medical Association. For large species the pulse, respiratory rate, mucuous membrane color and temperature should be monitored on a routine basis. Monitoring anesthesia in rodents is possible but the small size of rodents precludes the use of several methods to monitor anesthesia commonly used in larger species.

Normal physiologic parameters of laboratory animals:
Mouse, Rat, Rabbit, Guinea pig, Sheep/goats, Dog, Cat, Macaque

Sheep/goats

Heart rate 70-80 (adult); 115 (lamb);
Respiratory Rate 12-15 (adult); 15-18 (lamb)
Perfusion Time of Oral Mucous Membranes 1-2 seconds
Rectal Temperature 38.5-40 C (adult); 38.5-40.5 (lamb)

Note: Ocular reflexes are of little value in monitoring depth of anesthesia in sheep. 25

Dog

Heart rate, large breed-adult 60-80
Heart rate, small breed-adult 80-120
Heart rate, young dog 110-120
Respiratory Rate, old dog 14-16
Respiratory Rate, young dog 20-22
Perfusion Time of Oral Mucous Membranes < 2 seconds
Rectal Temperature 37.5-39 C ; 99.5-102.2 F
PaO2 70-95
PaCO2 40-50
pH 7.3-7.4

Cat

Heart rate, adult 130-140
Heart rate, young 100-120
Respiratory Rate 20-30
Perfusion Time of Oral Mucous Membranes < 2 seconds
Rectal Temperature 8-39.5 C; 100.4-103.1 F
PaO2 70-95
PaCO2 25-35
pH 7.3-7.4

Macaque

Heart rate - sedated 120-180
Respiratory Rate - sedated 32-50
Rectal Temperature 37-39.1 C; 99-102.5 F

 © 2002 The University of Iowa. All rights reserved.
Contact Information: donna-rayl@uiowa.edu
Last updated: 07/18/2002

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