NIH: Framework Programs for Global Health Innovation (D43)

Program Summary

The purpose of this FOA is to provide support for the development of broadly interdisciplinary training programs in global health directed towards encouraging innovation in products, processes, and policies. Trainees should be at the postdoctoral level or have attained a terminal degree in their fields. Training projects should identify critical health needs in Low and Middle Income Countries (LMICs) that can be addressed through Innovation, and carry out the scientific research necessary to develop, validate, and test their concepts. To increase the translation of research findings into realized health benefits, project design should include considerations of implementation appropriate to low resource settings in LMICs, particularly regarding increased effectiveness, affordability, accessibility, ease of use or delivery, and/or scalability. This FOA emphasizes hands-on, problem-solving, and collaborative approaches and allows U.S. and LMIC trainees to be trained together. By engaging multiple entities within and among institutions, the proposed programs should also build institutional capacity for interdisciplinary training in global health, stimulate new collaborations, and increase the pipeline of researchers from a wide variety of fields who engage in global health research.


Only one application per institution (normally identified by having a unique DUNS number or NIH IPF number) is allowed. However, institutions may participate in more than one consortium, and may be both an applicant institution and a participating consortium partner.

Requirement for Interdisciplinary Participation: Participation by a minimum of three Schools, departments, or other entities representing distinct disciplines is required. Subspecialties within a field, such as Medicine, would not qualify as distinct disciplines. For consortia, the three disciplines may be distributed among the partner academic or research institutions. If there is any question about whether disciplines are distinct, please contact the FIC Scientific Contact (Section VII.1).

Pre-requisite activities in Global Health: Institutions or consortia are eligible to apply if they participate, as a recipient or significant collaborator, on a minimum of five research or research training grants or research contracts in global health topics involving significant participation by investigators in LMICs (as defined by the World Bank, above), such as a role as Program Director(s)/ Principal Investigator(s) (PD(s)/PI(s)) or key personnel or as a listed performance site. All of these awards should be from funding sources external to the institution and should be active on the application receipt date for this FOA, with at least two of these awards from the NIH. NIH R03 awards, however, do not count as qualifying grants. . If a consortium of institutions applies as partners, the institutions applying may together meet this pre-requisite (i.e. as the sum of all the partners). These pre-requisite grants are not intended to act as "parent grants" for the training program, as the training models proposed will likely not fit easily within established research programs. Indeed, in some cases this might un-necessarily restrict the possibilities of the research questions asked and the training models explored. Rather they provide a metric of the expertise available in global health research at the institution and the ability of the entire consortium community to engage and provide mentorship for trainees. They may also provide a necessary network of international collaborations for training projects. Include a Table in the Research Training Program Plan that lists the qualifying grants and contracts, as detailed below under Section IV.2. If there are questions about qualifying grants or an institution’s eligibility, please contact the FIC Scientific Contact (Section VII.1

Institutional Commitment: Applications should include letters from the appropriate head research administrator at all participating institutions confirming the institutions' commitment to the proposed research training program. The institution(s) should state their commitment to overcoming any administrative obstacles to the implementation of the application, such as accommodation for participation by multiple Schools at the university or collaboration with other institutions. Appropriate institutional commitment to the program also includes the provision of adequate staff, facilities, and resources that can contribute to the planned program.

To comply with the limitation of one submission per institution, please contact Cheryl Ridgeway ( in the Office of the Vice President for Research if you are interested in submitting a formal proposal.

Date Due to DSP or UIF12/15/2011
Date Due to Sponsor12/15/2011
Required LOI Due DateN/A
Non-Required LOI Due DateN/A
Sponsor URL:

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